Health Osteonecrosis of the Jaw: A Rare Side Effect of Osteoporosis Therapy MrezaMkOctober 12, 2025030 views (MedPage Today) — Some of the most commonly used medications for osteoporosis can lead to osteonecrosis of the jaw (ONJ), a rare but serious side effect. “Inflammation and infection [in the mouth] plus a potent antiresorptive can lead to ONJ…